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Items where Subject is "Clinical Pharmacology and Therapeutics"

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Number of items: 144.

ANS and the lung

Lecture slides looking at the autonomic nervous system and the respiratory system

Acute asthma case

Case study task accompanying the respiratory pharmacology practical session

Alcohol: From Screening to dependence

Final session of alcohol and addiction week

An introduction to anti-viral and anti-fungal drugs

Slides accompanying lecture describing: viral replication; the mechanism of action of anti-virals and the points at which they have their effects; different types of fungi; the sites of action of antifungal drugs; the drugs to treat different fungal species

An introduction to drugs used to treat heart arrhythmias

Slides accompanying lecture on antiarrythmic drugs, covering: sodium channel blockers; beta adrenoceptor blockers; potassium channel blockers; calcium channel blockers; adenosine and atropine

An introduction to neurotransmitters

Slides accompanying lecture on neurotransmitters and the pharmacological management of CNS disorders


Slides accompanying lecture covering: how the body sense pain; the various drug groups involved in treating pain; the mechanism of action and the major adverse effects of these drugs

Anti-coagulant drugs

Slides accompanying lecture on anti-coagulant drugs including warfarin, heparins and other inhibitors of thrombin / factor X

Anti-convulsant (anti-epileptic) drugs

Slides accompanying lecture covering: types of epilepsy; stages of epilepsy; drugs that suppress focus and prevent spread; drugs that increase inhibitory pathways

Anti-depressant and mood stabilising drugs

Learning outcomes from this lecture: 1. describe indications for and phases of treatment of depressive illness 2. describe the mechanisms of action and properties of commonly used antidepressant drugs 3. summarise the potential benefits and risks of antidepressants 4. describe the indications for mood-stabilising drugs in treating patients with bipolar disorder 5. summarise the potential benefits and risks of mood stabilising drugs

Anti-malarial drugs

Slides accompanying lecture on malaria and the drugs used in its prevention and treatment

Anti-platelet drugs and thrombolytic drugs

Slides accompanying lecture on anti-platelet and thrombolytic drugs

Anti-psychotic drugs

Slides accompanying lecture on drugs used to treat psychosis

Anti-ulcer drugs

Slides accompanying lecture on drugs used in the treatment of indigestion (dyspepsia), duodenal and stomach ulcers and gastro oesophageal reflux disease (GORD)

Antibiotics 1 and 2

Combined slides accompanying lectures on antimicrobials and antibiotic resistance

Antibiotics case presentations

Slides accompanying antimicrobials tutorial, using case histories to decide on appropriate treatment for a range of infectious diseases.

Antibiotics case presentations - Questions

Antibiotics case presentations, accompanying pharmacology tutorial

Antibiotics, antibiotic resistance and management of infections in primary care

Lecture slides accompanying session on antibiotics and antibiotic resistance

Anticoagulants and Anti-platelet drugs (BM4)

Handout for 'Anticoagulants and anti-platelet drugs' lecture to support Tony Sampson's BM4 Year 1 lecture, in versions with 1,2,3 or 6 slides per page.

Antidepressant drugs

Slides accompanying lecture looking at drug strategies in the treatment of depression

Antimicrobials BM4

Slides accompanying lecture on antimicrobials covering: antibiotic resistance mechanisms; the targets and drug groups of antimicrobials; the antimicrobial mechanism of action; examples of first line uses for specific drugs

Anxiolytic and hypnotic drugs

Learning outcomes are to be able to: 1. name classes of drugs used in insomnia and anxiety disorders 2. describe properties of commonly used drugs 3. summarise potential hazards of pharmacological treatments pharmacological and psychological treatments


Slides accompanying session on arrhythmias, covering: pacemakers; mechanisms of arrhythmogenesis; consequences of arrhythmias; classification of heart rhythms

Assessing the critically ill or injured patient

An explanation of how to recognise a critically ill patient, and a structured approach to assessing and treating such a patient

Autistic Spectrum Disorders

Brief description: 1. Psychiatric history of someone with suspected autism, with investigations; 2. How did the concept of Autism/ Asperger's syndrome come about? (background); 3. Diagnosis and Questions to Ask a patient; 4. Conditions Autism may be confused with; 5. Benefits of a diagnosis; 6. What next/ post-diagnosis. Learning outcomes: 1. To be able to recognise criteria for diagnosing autism in a patient who may have this; 2. To understand that autism is a highly genetic disorder (always check family traits) and that neurobiological correlates are different than in the general population; 3. To appreciate the similarities with and differences between autism and other diagnoses in mental health; 4. To appreciate that: autism lies on a spectrum of severity, that it is relatively common; not an illness, but a disorder and only seen as such when it interferes with functioning (dysfunction being the tell-tale sign of whether to provide a diagnosis or not); 5. To appreciate that whilst medication cannot "treat" autism, CBT is helpful and interventions beginning in childhood even more effective.

Autonomic nervous system (ANS) 1

Lecture slides on the autonomic nervous system, covering the anatomy, key features, functions and divisions of the ANS

Autonomic nervous system (ANS) 2

Lecture slides on the autonomic nervous system, covering acetylcholine (ACh), noradrenaline (NA), and the impact of drugs on the ANS in relation to these.

Autonomic nervous system (ANS) 3

Lecture slides on the autonomic nervous system, covering adrenoceptors and beta-blockers

BM4 Pharmacokinetics lectures 1 and 2 handout

Lecture slides on pharmacokinetics, covering absorption, distribution, metabolism and excretion, and basic calculations.

BM5 Pharmacology of Angina and MI

Pharmacology lecture handout on nitrates, beta-blockers, calcium antagonists, plasminogen activators and other drugs in angina and myocardial infarction,

BM5 Pharmacology of Heart Failure

BM5 Y1 RCR1 lecture on diuretics, ACEI/ARA, digoxin, beta-blockers and other drugs in heart failure

Beta-blocker practical class - lab protocol

Handout accompanying pharmacology practical looking at whether beta blockers significantly reduce the workload of the heart at rest and during exercise

Beta-blocker practical: Introductory slides

Slides introducing cardiovascular pharmacology practical exploring the effects of beta-blockers

Cardiovascular pharmacology tutorial - angina and myocardial infarction

Question sheet accompanying cardiovascular pharmacology tutorial

Clinical aspects of liver disease

Lecture slides from the liver symposium

Clinical aspects of type 1 diabetes

Slides accompanying lecture giving an overview of diabetes mellitus, looking at what diabetes is and how it is diagnosed and classified.

Clinical problems in early pregnancy

Slides accompanying lecture

Clinical problems in late pregnancy

Slides accompanying lecture.

Cystic fibrosis: new therapies

Slides accompanying lecture on cystic fibrosis

Cytotoxic drugs 1

Slides accompanying first of two lectures on anti-cancer drugs

Cytotoxics BM4

Drugs used in the treatment of cancer

Diabetes: treatment and complications

Overview for Diabetes SBOM by Prof R Holt


Slides accompanying lecture covering: the function of the kidney; the targets for drug therapy in diuresis; the drugs used in diuresis, their side effects and their first line uses

Drug calculations worksheet

Question sheet accompanying the BM5 Y1 problem solving session

Drugs for Parkinsonism

Slides accompanying tremor symposium, covering: how Parkinson's pathophysiology is modified by drugs; all drugs classes used in Parkinson's; adverse effects and how to counter them

Drugs for Parkinsonism

Slides accompanying lecture on the drugs used to treat Parkinson's disease

Drugs in nausea, vomiting and migraine

Slides accompanying lecture covering: the aetiology of nausea, vomiting and migraine; the drugs used to treat these; the mechanism of action, side effects and therapeutic uses

Drugs in pregnancy and lactation

Slides accompanying lecture on drugs in pregnancy

Drugs used in hypertension

Slides accompanying lecture on anti-hypertensive drugs, covering: control of blood pressure and the mechanism of hypertension; consequences of elevated blood pressure; drugs used to reduce blood pressure, their site of action and potential side effects

Drugs used in the treatment of indigestion (dyspepsia), duodenal and stomach ulcers and gastro oesophageal reflux disease (GORD) BM4

Slides accompanying session describing the diseases of dyspepsia, GORD and peptic ulcer, and the drugs used to treat these

Emergency contraception

Slides accompanying contraception symposium, covering the three forms of emergency contraception: copper intrauterine devices; levonorgestrel; ulipristal

Eye Practical Consent Form

This consent form is to be printed out, signed and brought to the practical session to allow the participants to receive eye drops as part of the practical class

Eye pharmacology practical - introductory slides

Slides accompanying pharmacology practical

Eye pharmacology practical - poster

Poster presentation linking the physiology, pathology, anatomy and pharmacology of some conditions in the human eye

Eye pharmacology practical: the actions of drugs on the human eye

Handout accompanying pharmacology practical

GI Pharmacology Tutorial

This tutorial will help you to place a range of drugs covered throughout the GI course

GI pharmacological practical poster material

Poster material accompanying gastrointestinal pharmacology practical

GI pharmacology practical class

Handout accompanying gastrointestinal pharmacology practical

General anaesthetics

Slides accompanying lecture covering: history of anaesthesia; stages of anaesthesia; mechanism of action of general anaesthetics; pharmacokinetics of intravenous and inhaled anaesthetics; pharmacodynamics and uses of general anaesthetics

Heart failure

Slides accompanying symposium on heart failure

Hormonal contraception

Slides accompanying contraception symposium, covering the role of oestrogen and progesterone in the menstrual cycle; the mechanism of action of combined and single hormonal methods of contraception and their side effects

Inflammatory bowel disease symposium

Combined slides accompanying IBD symposium, covering the pathology, immunology, pharmacology and clinical aspects of IBD and coeliac disease

Inflammatory bowel disease symposium BM4

Slides accompanying symposium on the pathology, immunology, pharmacology and clinical aspects of inflammatory bowel disease (IBD)

Information on the PSA (and SCRIPT) for Years 3 and 4.

Handout from the lecture on the PSA and SCRIPT given at the introduction to clinical attachments in January of BM5/6 Year 3. Also applicable to Year 4 students, and corresponding years of BM(EU) and BM4.

Information on the PSA for Final Year students

A reminder about the online PSA in Final Year, including what you need to bring on the day and other information. See also other Medshare resources by searching for PSA.

Introduction to Pain Week

Contains 1. Overview of the field 2. Case (video) 3. Supporting information for the case 4. Resources for the supporting information a. Sciatica Option Grid b. NICE neuropathic pain pathway c. Startback d. Pain Management Programmes information 5. REsources for introductory lecture a.CMO England report on Pain

Introduction to Prescribing (Prescribing Safely SBOM)

An introduction to the principles of drug prescribing, by Riehanh Khan. For BM5/6/EU Year 1 students.

Introduction to clinical pharmacology and therapeutics 1 and 2 (BM4)

Intro slideset 1 is for PRE-ARRIVAL review before BM4 Week 1. Slideset 2 is for the lecture in Week 1.

Lipid-lowering drugs

Slides accompanying lecture on lipid-lowering drugs, including statins, fibrates, nicotinic acid and anion-exchange resins

Local anaesthetics

Slides accompanying lecture covering the mechanism of action, pharmacokinetics and uses and methods of administration of local anaesthetics

Mood Disorders

The aim of this lecture is to enable students: 1. To be able to define major depression and bipolar affective disorder 2. To be able to describe the natural history of mood disorders 3. To be able to describe some of the proposed aetiology of mood disorders 4. To relate the proposed neurobiology of mood disorders to your understanding of neurophysiology

Myocardial infarction

Slides accompanying clinical symposium on myocardial infarction

Narcotic analgesics: opioids

Slides accompanying lecture covering: the pathophysiology of pain; opioid receptors; analgesic uses of opioids; non-analgesic effects of opioids; opioid tolerance and dependence

Non-steroidal anti-inflammatory drugs (NSAIDs)

Slides accompanying lecture covering: the history of NSAIDs; roles of prostaglandins; cyclo-oxygenases (COX); adverse effects of NSAIDs; clinical uses of NSAIDs

Peptic ulcer symposium BM4

Slides accompanying symposium covering various aspects of GI diseases and their treatment

Peptic ulcer symposium BM5 BMEU

Combined slides accompanying the peptic ulcer symposium, covering: Helicobacter pylori; Gastro-oesophageal reflux & Barrett’s oesophagus; Dyspepsia, ulcers, reflux and public health; Diagnosis and management of upper GI diseases; Drug treatments

Peripheral Vascular Disease

Handout for Dr Derek Waller's pharmacology lecture in the Peripheral Vascular Disease clinical symposium

Pharmacokinetics (Drug Interactions) Practical Poster

Poster describing the types and mechanisms of drug interactions. Used in the PK practical.

Pharmacokinetics (Drug Interactions) Practical: Questions

Patient cases and questions for the pharmacokinetics practical

Pharmacokinetics (Drug Monitoring) Tutorial

Questions for the BM Year 1 Foundations module pharmacology tutorial on drug monitoring

Pharmacokinetics 1

First of four lectures on Pharmacokinetics in Foundations module. Covers administration and absorption of drugs.

Pharmacokinetics 2

Second of four lectures on Pharmacokinetics in Foundations module. Covers drug distribution and metabolism.

Pharmacokinetics 3

Third of four pharmacokinetics lectures in Foundations course

Pharmacokinetics 4

Last of four pharmacokinetics lectures in BM Year 1 Foundations module

Pharmacological aspects of preterm labour

Slides accompanying symposium on premature labour, discussing the management of preterm labour, the treatments for preventing preterm labour, and their limitations

Pharmacology 1: What is Pharmacology?

First of three introuctory pharmacology lectures in BM5 Y1 Foundations of Medicine by Dr Sampson

Pharmacology 2: What is a Drug?

Second of three introductory lectures on basic pharmacology: handout 6 slides per page

Pharmacology 3: How do drugs work?

Third of three introductory lectures on basic pharmacology by Dr Sampson for BM5/6/EU Year 1 students

Pharmacology Revision Lecture for BM5 Year 1 Semester 2 (NLM1/RCR1)

Lecture from BM5 Year 1 Semester 2 with key slides from pharmacology lectures in NLM1 and RCR1.

Pharmacology of Heart failure (BM4)

Handout from Tony Sampson for BM4 lecture on 'Pharmacology of Heart Failure', in versions with 1,2,3 or 6 slides per page.

Pharmacology of Hypertension (BM4)

Handout for anti-hypertensive drugs lecture by Tony Sampson, in versions with 1,2,3 or 6 sliders per page

Pharmacology of Labour - fill in the blanks student form

Formative assessment of Pharmacology of labour to be completed by students during the Physiology and Pharmacology of Labour lecture

Pharmacology of Myocardial Infarction (BM4)

Handout for BM4 lecture by Tony Sampson on drugs for angina and myocardial infarction, and statins, in versions with 1,2,3 or 6 slides per page.

Pharmacology of addictive substances

Slides accompanying lecture describing the main drugs of abuse; the main effects of drugs of abuse on the CNS; dependence and the major pharmacological approaches to treating opioid, nicotine and alcohol dependence

Pharmacology of angina

Slides accompanying clinical symposium on angina

Pharmacology of asthma

Slides accompanying lecture on asthma relievers and preventers

Pharmacology of breast cancer tutorial

Question sheet accompanying pharmacology tutorial on breast cancer and cytotoxic drugs

Pharmacology of corticosteroids

Slides accompanying lecture on the pharmacology of corticosteroids

Pharmacology of diarrhoea and constipation

Slides accompanying lecture describing: the causes of acute and chronic diarrhoea; the processes involved in constipation; the drugs used to treat diarrhoea and constipation and the mechanism of action of these

Pharmacology of smoking

Lecture slides accompanying session on the effects of smoking and smoking-related diseases

Pharmacology of steroids

Slides accompanying lecture focussing mainly on the steroid sex hormones and drugs that modify them, covering: oestrogens; progestogens; oral contraceptive pill (OCP); aromatase inhibitors & anti-oestrogens; testosterone and anti-androgens; anabolic-androgenic steroid drugs

Pharmacology of the autonomic nervous system

Slides accompanying pharmacology lecture on the autonomic nervous system (ANS)

Pharmacology of the neuromuscular junction

Slides accompanying lecture on the pharmacology of the neuromuscular junction (NMJ)

Physiology and pharmacology of labour

Slides accompanying lecture discussing: the process of labour; control of uterine activity; how the fetus matures in readiness for life after birth; pain relief during labour

Pin the tail on the donkey

Drug side effects task accompanying respiratory pharmacology practical session

Positive Inotropes (and Vasopressors)

A lecture to introduce some of the commoner drugs used clinically to manipulate the cardiovascular system and their mode of action

Positive inotropic drugs

Slides accompanying lecture on positive inotropic drugs

Premature labour symposium: Neonatal perspective

Slides accompanying symposium on premature labour

Problem solving and data manipulation

BM5 Y1 lecture slides looking at the calculations used in prescribing drugs

Psychiatry revision lecture

psychosis, mood disorders, anxiety, alcohol, autism, ADHD - overview and some questions. Please note, this is not a comprehensive summary, rather a memory aid. Note there is no old age psychiatry included in this lecture, but you should revise this as well.

Renal pharmacology tutorial - diuretics in heart failure

Question sheet accompanying renal pharmacology tutorial on diuretics

Reproductive pharmacology tutorial

Question sheet accompanying tutorial on oral contraceptives and drugs in pregnancy

Respiratory pharmacology 1

Slides accompanying lecture on respiratory pharmacology, covering: asthma; reliever drugs; preventer drugs (specifically corticosteroids)

Respiratory pharmacology 2

Slides accompanying lecture on respiratory pharmacology, covering: preventer drugs; compliance; oral vs inhaled routes; acute and chronic asthma; COPD

Respiratory pharmacology practical class

Handout accompanying practical session on respiratory pharmacology

Respiratory pharmacology tutorial

Question sheet accompanying tutorial on respiratory pharmacology

SCRIPT safe prescriber: registration

Information on SCRIPT software for BM4/BM5/BM6 and BM(EU) students doing clinical modules in their later years, in preparation for the Prescribing Safety Assessment (PSA)


Slides accompanying lecture on aspects of shock, including: causes; pathological changes; physiological mechanisms; inotropic drugs; disorders of acid-base balance; antimicrobial therapy

Skin prick testing

Slides accompanying respiratory pharmacology practical session, showing skin prick testing for allergy

Southampton Student Formulary

Classified list of core drugs for Southampton medical students, based on the national student formulary from the clinical section of the BPS, with adaptations. This is an overall guide to the key drugs (and drug groups) prescribed by FY1/FY2 doctors. It does not absolutely define or restrict what is taught and it is subject to updating at any time. Also includes the Top 12 Drug Groups and the Top 40 Individual Drugs. See also the book "The Top 100 Drugs" by Hitchings, Lonsdale, Burrage & Baker (Churchill-Livingstone, 2015).

Steroidal contraception

Summary table listing the action, adverse effects, benefits, indications and contraindications for different forms of steroidal contraception.

Summary of the known major neurotransmitters

Table explaining the function of the main neurotransmitters, the effect of deficit and surplus for each, and how drugs can effect synaptic transmission


Slides accompanying lecture on the electrocardiogram (ECG)

The Prescribing Safety Assessment (PSA): Learning Resources.

A document which provides general information and links to key external websites and learning resources (particularly SCRIPT) to help you prepare for the PSA as you progress through your programme.

The Trip Pharmacology of GI

No description.

The operation: anaesthetics and other drugs commonly used during elective surgery

This tutorial on an elective surgical procedure brings together a number of drug groups covered in the Nervous & Locomotor courses 1 and 2, including General Anaesthetics, Opiates, Anti-Muscarinics, NMJ blockers, AChEsterase inhibitors, and BDZ sedatives.

The oral route vs the inhaled route for asthma therapy

Poster from the respiratory pharmacology practical, examining the advantages and disadvantages of oral and inhaled routes for asthma therapy.

Toxicology of Drugs

BM5 Year 1 lecture by Dr Spiro Garbis

Tutorial on Parkinson's drugs and anti-psychotic drugs

Question sheet accompanying pharmacological tutorial

Tutorial on anti-depressants and sedatives

Question sheet accompanying pharmacology tutorial

Tutorial on neuromuscular junction (NMJ) pharmacology

Question sheet for pharmacology tutorial on the neuromuscular junction

Tutorial on pain relief in palliative care

Question sheet accompanying pharmacology tutorial

Tutorial on pharmacology of COPD and smoking cessation

Question sheet accompanying pharmacology tutorial on COPD

This list was generated on Sat Sep 23 22:43:28 2017 BST.